AMD Instinct MI355XvsAMD Instinct MI300X
AMD Instinct MI355X vs AMD Instinct MI300X: Specs, Benchmarks & Cloud Pricing
Full technical comparison of AMD Instinct MI355X and AMD Instinct MI300X — VRAM, memory bandwidth, FP16 TFLOPS, TDP, and live cloud pricing across all providers. Updated July 2026.
Technical Specifications
Spec
AMD Instinct MI355X
AMD Instinct MI300X
Architecture
CDNA 4
CDNA 3
VRAM
288 GB HBM3e
192 GB HBM3
Memory bandwidth
8,000 GB/s
5,300 GB/s
FP16 performance
2,615 TFLOPS
1,307 TFLOPS
TDP
750 W
750 W
NVLink support
No
No
Release year
2025
2023
Green = better value for that metric.
AMD Instinct MI355X
The AMD Instinct MI355X is AMD's CDNA 4 flagship.
Best For
- Large LLM inference
- Agent workloads
- Memory-bound AI
AMD Instinct MI300X
The AMD MI300X leads all GPUs on memory capacity (192GB HBM3) and bandwidth (5.3 TB/s), making it exceptional for serving very large language models that don't fit on H100.
Best For
- Memory-bound LLM inference
- Large model serving
- HPC