AMD Instinct MI250XvsNVIDIA A100 80GB
AMD Instinct MI250X vs NVIDIA A100 80GB: Specs, Benchmarks & Cloud Pricing
Full technical comparison of AMD Instinct MI250X and NVIDIA A100 80GB — VRAM, memory bandwidth, FP16 TFLOPS, TDP, and live cloud pricing across all providers. Updated July 2026.
Technical Specifications
Spec
AMD Instinct MI250X
NVIDIA A100 80GB
Architecture
CDNA 2
Ampere
VRAM
128 GB HBM2e
80 GB HBM2e
Memory bandwidth
3,277 GB/s
2,039 GB/s
FP16 performance
383 TFLOPS
312 TFLOPS
TDP
560 W
400 W
NVLink support
No
Yes
Release year
2021
2020
Green = better value for that metric.
AMD Instinct MI250X
The AMD Instinct MI250X is AMD's CDNA 2 data center GPU.
Best For
- HPC workloads
- Large model inference
- AMD ROCm deployments
NVIDIA A100 80GB
The A100 remains one of the most widely available data center GPUs. Its broad provider support and mature software ecosystem make it a reliable choice for ML training and inference.
Best For
- ML training
- Inference at scale
- HPC