Rent MI250X 128GB
Compare live on-demand and spot rental prices across 97+ cloud providers. Dual-die AMD CDNA 2 GPU. 128GB HBM2e across two dies. Predecessor to MI300X. Available on AWS (p4de) and select cloud providers at competitive pricing.
Choosing the right billing model for MI250X 128GB
Provision and terminate at any time. Ideal for development, short experiments, and workloads with unpredictable duration.
Instances can be reclaimed when demand spikes. Best for fault-tolerant batch jobs, training with checkpointing, and preprocessing.
Lock in a rate for 1–3 months. Right for sustained production inference or long training runs where cost predictability matters.
Best use cases
- Large model training
- Memory-bound HPC
- AMD ROCm workloads
MI250X 128GB — Specs & Benchmarks
Performance bars, compute tiers (FP32/FP16/BF16/FP8/INT8), memory specs, LLM model size guidance, and related GPU comparisons.
MI250X 128GB Rental Guide
Renting the MI250X 128GB makes sense when your workload requires 128GB of HBM2e memory and 383 TFLOPS of FP16 compute. The most common use cases are Large model training, Memory-bound HPC, AMD ROCm workloads. Before committing to a rental, verify that your model and batch size fit within 128GB — a 70B parameter model requires approximately 140GB at FP16, which would require two MI250X 128GB instances with tensor parallelism.
For fault-tolerant batch workloads — preprocessing, offline inference, or training with checkpointing — spot instances typically save 40–70% vs on-demand rates. The MI250X 128GB's 128GB VRAM makes it well-suited for long-running batch jobs where interruption recovery is manageable. On-demand instances give you full control with no commitment — ideal for development, short experiments, and workloads with unpredictable duration. Most providers bill per second or per minute, so short jobs are not penalized by hourly minimums.
Reserved pricing (1–3 month commitments) makes sense if you have a predictable, sustained workload. For development, experimentation, or variable-volume inference, on-demand remains the most flexible choice. When comparing providers, look beyond the headline hourly rate: check region availability (latency matters for interactive inference), spot interruption frequency, and whether the provider offers per-second billing. Use the GPU cost calculator to model total cost across different billing models and utilization rates before choosing a provider.
Frequently Asked Questions
How much does it cost to rent a MI250X 128GB?
MI250X 128GB on-demand rental prices vary by provider and region. On-demand rates typically range based on availability and provider margins — use the comparison table above to see current live rates across all providers. Spot instances are generally 40–70% cheaper than on-demand but can be interrupted. Monthly cost estimates (hourly rate × 730 hours) are shown in the table for sustained workloads.
Which cloud provider has the cheapest MI250X 128GB?
The cheapest MI250X 128GB provider changes as providers update their pricing. The comparison table above shows live rates sorted by price, so the cheapest option is always at the top. Factors beyond headline price include region (latency to your users), availability (high/medium/low), and billing granularity (per-second vs per-hour minimums).
What can I run on a MI250X 128GB?
With 128GB of HBM2e, the MI250X 128GB can run LLM models up to approximately 64B parameters at FP16, 128B at INT8, or 256B at INT4/GGUF quantization. Common workloads include: Large model training, Memory-bound HPC, AMD ROCm workloads. Dual-die AMD CDNA 2 GPU. 128GB HBM2e across two dies. Predecessor to MI300X. Available on AWS (p4de) and select cloud providers at competitive pricing.
Should I use on-demand or spot pricing for MI250X 128GB?
Spot instances save 40–70% vs on-demand but can be interrupted when the provider needs capacity back. Use spot for: batch inference jobs, training runs with checkpointing, preprocessing pipelines, and any workload that can tolerate interruption and restart. Use on-demand for: production inference serving, interactive workloads, and jobs that cannot be interrupted. Most providers bill per second, so short on-demand jobs are not penalized by hourly minimums.
How does the MI250X 128GB compare to the H100 for cloud rental?
The H100 80GB delivers 1,979 TFLOPS FP16 with 3,350 GB/s HBM3 bandwidth, compared to the MI250X 128GB's 383 TFLOPS FP16 and 3277 GB/s bandwidth. The H100 is significantly more expensive — typically $2.50–$5.00/hr vs lower rates for the MI250X 128GB. For workloads that fit within 128GB and don't require FP8 precision, the MI250X 128GB often delivers better cost-per-token than the H100.
What is the memory bandwidth of the MI250X 128GB and why does it matter?
The MI250X 128GB has 3277 GB/s of memory bandwidth. For LLM inference, memory bandwidth is often more important than raw TFLOPS — each autoregressive token generation reads the full model weight matrix from VRAM, so bandwidth directly determines tokens-per-second throughput. Higher bandwidth means faster inference for the same model at the same batch size. For batch inference (processing many requests simultaneously), compute throughput becomes more important.
Can I use the MI250X 128GB for Stable Diffusion or image generation?
Yes — the MI250X 128GB is capable for Stable Diffusion and image generation workloads. Image generation is primarily FP32 and FP16 compute-bound, and the MI250X 128GB's 47.9 TFLOPS FP32 throughput determines images-per-second. The 128GB VRAM fits SDXL (requires ~6GB) and most ControlNet pipelines. For high-throughput image generation at scale, compare cost-per-image across providers using the GPU cost calculator.