CDNA 4
AMD Instinct MI355X
wins
4
The AMD Instinct MI355X is AMD's CDNA 4 flagship.
Ada Lovelace
NVIDIA RTX 4060 Ti 16GB
wins
1
The RTX 4060 Ti 16GB doubles the VRAM of the RTX 4060 at 16GB GDDR6, enabling 7B–13B model inference at INT4/INT8.
Performance comparison
Visual bars — winner highlighted
AMD Instinct MI355X
Metric
NVIDIA RTX 4060 Ti 16GB
FP16 TFLOPS
Bandwidth
VRAM
TDP (lower=better)
TFLOPS/watt
GB/s per watt
Full specification table
| Spec | AMD Instinct MI355X | NVIDIA RTX 4060 Ti 16GB |
|---|---|---|
| Architecture | CDNA 4 | Ada Lovelace |
| VRAM | 288 GB HBM3e | 16 GB GDDR6 |
| VRAM type | HBM3e | GDDR6 |
| Memory bandwidth | 8,000 GB/s | 288 GB/s |
| FP16 TFLOPS | 2,615 TFLOPS | 44.2 TFLOPS |
| TDP | 750 W | 165 W |
| TFLOPS/watt | 3.49 T/W | 0.27 T/W |
| GB/s per watt | 10.67 GB/s/W | 1.75 GB/s/W |
| NVLink | No | No |
| Release year | 2025 | 2023 |
Live cloud pricing
On-demand pricing across providers — updated in real time
Power efficiency analysis
TFLOPS/watt and GB/s/watt — critical for data center TCO
AMD Instinct MI355X
NVIDIA RTX 4060 Ti 16GB
TFLOPS/watt measures compute efficiency — how much AI throughput you get per watt of power consumed. For data centers with PUE of 1.2–1.5, a 10% improvement in TFLOPS/watt translates directly to lower electricity costs and cooling requirements. GB/s/watt measures memory bandwidth efficiency, which is the binding constraint for memory-bound LLM inference workloads.
When to choose each GPU
Choose AMD Instinct MI355X for:
- Large LLM inference
- Agent workloads
- Memory-bound AI
Weaknesses / Limitations
- ROCm ecosystem less mature than CUDA — some frameworks require porting
- Very limited cloud availability compared to NVIDIA equivalents
- 750W TDP — high power draw comparable to H100 SXM
Choose NVIDIA RTX 4060 Ti 16GB for:
- Budget inference
- Small model fine-tuning
- Entry Ada AI
Weaknesses / Limitations
- Low bandwidth (288 GB/s) — inference throughput bottleneck
- 16 GB VRAM ceiling — cannot run 34B+ models
- Consumer GPU — no ECC memory or enterprise support
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