Compute Comparison
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CDNA 4

AMD Instinct MI355X

wins

4

The AMD Instinct MI355X is AMD's CDNA 4 flagship.

Large LLM inferenceAgent workloadsMemory-bound AI

Ampere

NVIDIA RTX A6000

wins

1

The RTX A6000 is NVIDIA's Ampere professional workstation GPU with 48GB GDDR6 and NVLink support.

Professional workstation AILarge model inferenceRendering

Performance comparison

Visual bars — winner highlighted

AMD Instinct MI355X

Metric

NVIDIA RTX A6000

FP16 TFLOPS

2.6k T
154 T

Bandwidth

8.0k GB/s
768 GB/s

VRAM

2.9k GB
486 GB

TDP (lower=better)

750 W
300 W

TFLOPS/watt

3.49
0.51

GB/s per watt

10.67
2.56

Full specification table

SpecAMD Instinct MI355XNVIDIA RTX A6000
ArchitectureCDNA 4Ampere
VRAM288 GB HBM3e48 GB GDDR6
VRAM typeHBM3eGDDR6
Memory bandwidth8,000 GB/s768 GB/s
FP16 TFLOPS2,615 TFLOPS154 TFLOPS
TDP750 W300 W
TFLOPS/watt3.49 T/W0.51 T/W
GB/s per watt10.67 GB/s/W2.56 GB/s/W
NVLinkNoYes
Release year20252020

Live cloud pricing

On-demand pricing across providers — updated in real time

Per hourPer GB VRAM/hr
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Power efficiency analysis

TFLOPS/watt and GB/s/watt — critical for data center TCO

AMD Instinct MI355X

FP16 TFLOPS2,615 TFLOPS
TDP750 W
TFLOPS/watt3.487 T/W
GB/s per watt10.67 GB/s/W

NVIDIA RTX A6000

FP16 TFLOPS154 TFLOPS
TDP300 W
TFLOPS/watt0.513 T/W
GB/s per watt2.56 GB/s/W

TFLOPS/watt measures compute efficiency — how much AI throughput you get per watt of power consumed. For data centers with PUE of 1.2–1.5, a 10% improvement in TFLOPS/watt translates directly to lower electricity costs and cooling requirements. GB/s/watt measures memory bandwidth efficiency, which is the binding constraint for memory-bound LLM inference workloads.

When to choose each GPU

Choose AMD Instinct MI355X for:

  • Large LLM inference
  • Agent workloads
  • Memory-bound AI

Weaknesses / Limitations

  • ROCm ecosystem less mature than CUDA — some frameworks require porting
  • Very limited cloud availability compared to NVIDIA equivalents
  • 750W TDP — high power draw comparable to H100 SXM

Choose NVIDIA RTX A6000 for:

  • Professional workstation AI
  • Large model inference
  • Rendering

Weaknesses / Limitations

  • Older Ampere architecture — lower TFLOPS than Ada equivalents at same VRAM
  • GDDR6 bandwidth (768 GB/s) lower than HBM-based GPUs
  • Superseded by RTX 6000 Ada and RTX PRO 6000 on new deployments