Compute Comparison
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CDNA 2

AMD Instinct MI250X

wins

4

The AMD Instinct MI250X is AMD's CDNA 2 data center GPU.

HPC workloadsLarge model inferenceAMD ROCm deployments

Volta

NVIDIA V100 32GB

wins

1

The V100 was NVIDIA's flagship AI GPU before the A100.

Legacy ML trainingBudget HPCMature framework support

Performance comparison

Visual bars — winner highlighted

AMD Instinct MI250X

Metric

NVIDIA V100 32GB

FP16 TFLOPS

383 T
125 T

Bandwidth

3.3k GB/s
900 GB/s

VRAM

1.3k GB
322 GB

TDP (lower=better)

560 W
300 W

TFLOPS/watt

0.68
0.42

GB/s per watt

5.85
3.00

Full specification table

SpecAMD Instinct MI250XNVIDIA V100 32GB
ArchitectureCDNA 2Volta
VRAM128 GB HBM2e32 GB HBM2
VRAM typeHBM2eHBM2
Memory bandwidth3,277 GB/s900 GB/s
FP16 TFLOPS383 TFLOPS125 TFLOPS
TDP560 W300 W
TFLOPS/watt0.68 T/W0.42 T/W
GB/s per watt5.85 GB/s/W3.00 GB/s/W
NVLinkNoYes
Release year20212018

Live cloud pricing

On-demand pricing across providers — updated in real time

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Power efficiency analysis

TFLOPS/watt and GB/s/watt — critical for data center TCO

AMD Instinct MI250X

FP16 TFLOPS383 TFLOPS
TDP560 W
TFLOPS/watt0.684 T/W
GB/s per watt5.85 GB/s/W

NVIDIA V100 32GB

FP16 TFLOPS125 TFLOPS
TDP300 W
TFLOPS/watt0.417 T/W
GB/s per watt3.00 GB/s/W

TFLOPS/watt measures compute efficiency — how much AI throughput you get per watt of power consumed. For data centers with PUE of 1.2–1.5, a 10% improvement in TFLOPS/watt translates directly to lower electricity costs and cooling requirements. GB/s/watt measures memory bandwidth efficiency, which is the binding constraint for memory-bound LLM inference workloads.

When to choose each GPU

Choose AMD Instinct MI250X for:

  • HPC workloads
  • Large model inference
  • AMD ROCm deployments

Weaknesses / Limitations

  • Older CDNA 2 architecture — lower FP16 TFLOPS than MI300X or H100
  • ROCm software ecosystem less mature than CUDA
  • 560W TDP — high power draw for its performance tier

Choose NVIDIA V100 32GB for:

  • Legacy ML training
  • Budget HPC
  • Mature framework support

Weaknesses / Limitations

  • Volta architecture — significantly lower TFLOPS than A100 or H100
  • 32 GB VRAM ceiling limits modern LLM workloads
  • No BF16 support — less efficient for modern transformer training